To start using your Trezor hardware wallet, go to trezor.io/start. Begin by connecting your device to a computer or smartphone. Follow the on-screen instructions to initialize your Trezor and create a secure PIN. Next, write down your recovery seed—this is crucial for restoring access if your device is lost or damaged. Install Trezor Bridge or Trezor Suite to manage your wallet easily. After setup, send a small amount of cryptocurrency to verify your wallet's functionality. Remember to keep your recovery seed safe and private, as anyone with access to it can potentially access your funds.